NAD+ supplements often include two companion compounds: quercetin and resveratrol. This guide explains what they are and why they're added to longevity formulas — as composition and rationale, not health claims.
For transparency: quercetin and resveratrol are plant compounds with no authorised UK health claims. This article describes what they are and why they're combined with NAD+ precursors — composition, not claims that they produce any health outcome.
What is quercetin?
Quercetin is a flavonoid — a type of polyphenol compound found naturally in many plant foods, such as onions, apples and capers. It's one of the more researched dietary flavonoids and is popular as a standalone supplement and as a companion in longevity formulas. In our NAD+ supplement, quercetin is included on a composition basis as part of a recognisable longevity blend.
Why is quercetin added to NAD+ supplements?
Honestly: it's included because it's a popular polyphenol in the longevity space and rounds out a comprehensive formula, not because we're claiming a specific effect. You'll see various mechanistic rationales discussed in the longevity community, but those are hypotheses and research interest — not authorised claims. We include it as a composition choice and describe it as exactly that.
What about quercetin and side effects?
Quercetin from food is consumed routinely and safely. As a concentrated supplement it's generally well-tolerated by healthy adults, though — as with any supplement — some people may be more sensitive, and quercetin can potentially interact with certain medications. If you take prescription medicine (or have a health condition), check with your GP or pharmacist before taking a concentrated quercetin supplement. That's the responsible step.
What is resveratrol?
Resveratrol is a polyphenol found in the skin of grapes, red wine and some berries. It's one of the best-known compounds in the longevity conversation and frequently appears alongside NAD+ precursors. It's fat-soluble, so it's sensibly taken with food containing some fat. Like quercetin, it's included in formulas on a composition basis.
Why are resveratrol and NAD+ precursors combined?
Resveratrol and NAD+ precursors (NR, NMN) are popular together in the longevity context, which is why formulas frequently pair them — our NMN Fusion Pro includes resveratrol, and our NAD+ supplement includes both quercetin and resveratrol. The pairing reflects a recognisable, comprehensive longevity composition. We're describing what's in the product and why those ingredients commonly go together — not promising an outcome.
The takeaway
Quercetin is a researched plant flavonoid and resveratrol is a grape-skin polyphenol; both are popular companions in NAD+/longevity formulas and are included on a composition basis, not because of authorised claims; and concentrated quercetin can interact with some medicines, so check with your GP if relevant. For the bigger picture, see our NAD+ guide.
Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. Concentrated quercetin and resveratrol can interact with some medications — if you take prescription medicine, speak to your GP or pharmacist first. If you are pregnant, breastfeeding or managing a medical condition, seek advice before starting a new supplement. Signed, Dr. Miron, Founder of Pure Vitamins UK.


